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Mahmoud E S Soliman Selected Research

autosomal dominant Spastic paraplegia 6

3/2021Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp3 values and favorable drug-like properties.

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Mahmoud E S Soliman Research Topics

Disease

26Neoplasms (Cancer)
11/2023 - 01/2015
9COVID-19
03/2023 - 01/2020
8Alzheimer Disease (Alzheimer's Disease)
02/2021 - 01/2018
6Carcinogenesis
12/2023 - 03/2018
6Tuberculosis (Tuberculoses)
04/2020 - 12/2016
5Malaria
11/2022 - 06/2018
5Neurodegenerative Diseases (Neurodegenerative Disease)
03/2022 - 01/2017
4Dengue (Dengue Fever)
09/2023 - 11/2014
3Glioma (Gliomas)
01/2023 - 05/2021
3Waldenstrom Macroglobulinemia (Macroglobulinemia)
10/2022 - 01/2022
3Infections
11/2020 - 01/2018
2Lung Neoplasms (Lung Cancer)
07/2023 - 01/2022
2Communicable Diseases (Infectious Diseases)
01/2023 - 10/2015
2Prostatic Neoplasms (Prostate Cancer)
12/2021 - 01/2020
2Nervous System Diseases (Neurological Disorders)
11/2021 - 01/2021
2Parkinson Disease (Parkinson's Disease)
03/2021 - 01/2021
2Inflammation (Inflammations)
03/2020 - 01/2015
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2019 - 03/2018
1Cardiovascular Diseases (Cardiovascular Disease)
05/2024
1Dyslipidemias (Dyslipidemia)
05/2024
1Carcinoma (Carcinomatosis)
12/2023
1Heart Failure
12/2023
1Triple Negative Breast Neoplasms
12/2023
1Neoplasm Metastasis (Metastasis)
11/2023
1Sarcoma (Soft Tissue Sarcoma)
01/2023
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
09/2022
1Lymphoma (Lymphomas)
07/2022
1Colorectal Neoplasms (Colorectal Cancer)
03/2022
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2022
1Lung Injury
01/2022
1Hyperglycemia
01/2022
1Diabetes Complications
01/2022
1B-Cell Lymphoma (Lymphoma, B Cell)
01/2022

Drug/Important Bio-Agent (IBA)

12EnzymesIBA
01/2023 - 01/2015
11Proteins (Proteins, Gene)FDA Link
12/2023 - 11/2014
6Peptide Hydrolases (Proteases)FDA Link
09/2023 - 11/2016
4LigandsIBA
12/2023 - 01/2018
4Monoamine Oxidase (MAO)IBA
03/2022 - 01/2017
3RNA-Dependent RNA Polymerase (RNA Dependent RNA Polymerase)IBA
03/2023 - 01/2018
3Poly (ADP-Ribose) Polymerase-1IBA
09/2022 - 01/2021
3TankyrasesIBA
09/2022 - 01/2019
3VaccinesIBA
01/2022 - 10/2015
3J147IBA
01/2020 - 06/2019
3Mitochondrial Proton-Translocating ATPases (Mitochondrial ATP Synthase)IBA
01/2020 - 06/2019
3plasmepsin (plasmepsin I)IBA
12/2019 - 06/2018
2LipidsIBA
05/2024 - 03/2020
2CateninsIBA
08/2023 - 03/2022
2vorasidenibIBA
01/2023 - 05/2021
2Agammaglobulinaemia Tyrosine KinaseIBA
01/2023 - 10/2022
2Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2023 - 05/2021
2Antiviral Agents (Antivirals)IBA
01/2022 - 10/2015
2bedaquiline (R207910)IBA
04/2020 - 01/2019
2Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
12/2019 - 11/2018
2Adenosine Triphosphate (ATP)IBA
09/2019 - 01/2019
2DNA (Deoxyribonucleic Acid)IBA
01/2019 - 12/2016
1PCSK9 InhibitorsIBA
05/2024
1LDL CholesterolIBA
05/2024
1antineoplaston A10 (A 10)IBA
12/2023
1N-decylphosphorylcholineIBA
12/2023
1Lapatinib (GW572016)FDA Link
12/2023
1Tyrosine Kinase InhibitorsIBA
12/2023
1AcidsIBA
11/2023
1Phosphotransferases (Kinase)IBA
11/2023
1Anaplastic Lymphoma KinaseIBA
07/2023
1ZincIBA
01/2023
1adagrasibIBA
01/2023
1isocitric acid (isocitrate)IBA
01/2023
1Proto-Oncogene Proteins c-mdm2IBA
01/2023
1Codon (Codons)IBA
01/2023
1sotorasibIBA
01/2023
1Oxidoreductases (Dehydrogenase)IBA
01/2023
1Oncogene Proteins (Oncogene Protein)IBA
01/2023
1Drug CombinationsIBA
11/2022
1artemisinin (artemisinine)IBA
11/2022
1Viral ProteinsIBA
11/2022
1PhytochemicalsIBA
11/2022
1fenebrutinibIBA
10/2022
1Mechlorethamine (Nitrogen Mustard)FDA Link
09/2022
1boron nitrideIBA
09/2022
1AluminumIBA
09/2022
1talazoparibIBA
09/2022
1ImidazolidinesIBA
09/2022
1venetoclaxIBA
07/2022
1QuinazolinonesIBA
03/2022
1Antimalarials (Antimalarial Agents)IBA
02/2022
1InterleukinsIBA
01/2022
1Matrix Metalloproteinases (MMPs)IBA
01/2022
1AntioxidantsIBA
01/2022
1Membrane Proteins (Integral Membrane Proteins)IBA
01/2022
1Aldehyde Reductase (Aldose Reductase)IBA
01/2022
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2022
1Deubiquitinating EnzymesIBA
01/2022
1ChlorineIBA
01/2022
1benzamideIBA
12/2021
1Temozolomide (Temodar)FDA LinkGeneric
10/2021

Therapy/Procedure

30Therapeutics
05/2024 - 11/2018
4Drug Therapy (Chemotherapy)
11/2022 - 01/2017
2Immunotherapy
01/2020 - 01/2020
1Traditional Medicine (Folk Remedies)
11/2022
1Castration
12/2021